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Assay Detail

CHEMBL681264

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the inhibition of Fucosyltransferase 4 alpha 1,3 at 8.5 uM GDP-fucose
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of inhibitors of -1,3-fucosyltransferase
Jefferies I, Bowen BR
Bioorg Med Chem Lett (1997) 7 : 1171 -1174
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.70 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL384759 1 5.30
CHEMBL2029050 1 4.09
CHEMBL2303733 1 -
CHEMBL314772 DEOXYFUCONOJIRIMYCIN 1 -
CHEMBL2029051 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL384759 IC50 = 5000.0 nM 5.30
CHEMBL2029050 IC50 = 81000.0 nM 4.09
CHEMBL2303733 IC50 = 233000.0 nM -
CHEMBL314772 DEOXYFUCONOJIRIMYCIN IC50 = 3500000.0 nM -
CHEMBL2029051 IC50 > 500000.0 nM -