Assay Detail
Binding
CHEMBL681340
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Compound was tested for inhibition of porcine endometrial estrogen sulfotransferase
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
In vitro inhibition of estrogen sulfoconjugation by some 2- and 4-substituted estra-1,3,5(10)-trien-17 beta-ols1a.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 4.97 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1627565 | — | — | 1 | 5.61 |
| CHEMBL1627689 | — | — | 1 | 5.12 |
| CHEMBL1627562 | — | — | 1 | 5.01 |
| CHEMBL1627977 | — | — | 1 | 4.99 |
| CHEMBL1627685 | — | — | 1 | 4.98 |
| CHEMBL1627697 | — | — | 1 | 4.92 |
| CHEMBL1627683 | — | — | 1 | 4.87 |
| CHEMBL1627690 | — | — | 1 | 4.83 |
| CHEMBL194749 | — | — | 1 | 4.79 |
| CHEMBL1627698 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1627565 | — | Ki | = | 2430.0 | nM | 5.61 |
| CHEMBL1627689 | — | Ki | = | 7510.0 | nM | 5.12 |
| CHEMBL1627562 | — | Ki | = | 9760.0 | nM | 5.01 |
| CHEMBL1627977 | — | Ki | = | 10200.0 | nM | 4.99 |
| CHEMBL1627685 | — | Ki | = | 10510.0 | nM | 4.98 |
| CHEMBL1627697 | — | Ki | = | 11900.0 | nM | 4.92 |
| CHEMBL1627683 | — | Ki | = | 13600.0 | nM | 4.87 |
| CHEMBL1627690 | — | Ki | = | 14800.0 | nM | 4.83 |
| CHEMBL194749 | — | Ki | = | 16300.0 | nM | 4.79 |
| CHEMBL1627698 | — | Ki | = | 25100.0 | nM | 4.60 |