Assay Detail
Binding
CHEMBL681441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Thermodynamic dissociation constant (KD) was measured upon binding to GAR TFase in mice
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Trifunctional purine biosynthetic protein adenosine-3 (CHEMBL3690) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
A multisubstrate adduct inhibitor of a purine biosynthetic enzyme with a picomolar dissociation constant.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.60 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL607957 | — | — | 1 | 9.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL607957 | — | Kd | = | 0.25 | nM | 9.60 |