Assay Detail
Binding
CHEMBL681792
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Glutamate uptake inhibition assay on glutamate transporters (excitatory amino acid transporters EAAT2) stably expressed on MDCK cells before U.V radiation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canis lupus familiaris |
| Cell Type | MDCK |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and photoreactivity of caged blockers for glutamate transporters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL79140 | — | — | 1 | 5.89 |
| CHEMBL177544 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL79140 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL177544 | — | IC50 | = | 124000.0 | nM | - |