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Assay Detail

CHEMBL682231

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Farnesyltransferase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Protein farnesyltransferase (CHEMBL2094108)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Identification of novel farnesyl protein transferase inhibitors using three-dimensional database searching methods.
Kaminski JJ, Rane DF, Snow ME, Weber L, Rothofsky ML, Anderson SD, Lin SL.
J Med Chem (1997) 40 : 4103 -4112
PubMed 9406600 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.80 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL335517 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL335517 IC50 = 16000.0 nM 4.80