Assay Detail
Functional
CHEMBL682255
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATP
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.37 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL355301 | — | — | 2 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL355301 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL355301 | — | IC50 | = | 43.0 | nM | 7.37 |