Assay Detail
Binding
CHEMBL682263
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Inhibitory concentration against Trypanosoma mexicana glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | trypanosoma mexicana |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.46 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3350919 | — | — | 1 | 7.22 |
| CHEMBL366942 | — | — | 1 | 5.70 |
| CHEMBL610238 | BETANMN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3350919 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL366942 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL610238 | BETANMN | IC50 | > | 500000.0 | nM | - |