Assay Detail
Binding
CHEMBL682619
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity was measured on recombinant human Glutathione S-transferase Mu 2
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 4.41 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301229 | — | — | 1 | 4.70 |
| CHEMBL58451 | — | — | 1 | 4.58 |
| CHEMBL58135 | — | — | 1 | 4.44 |
| CHEMBL60581 | — | — | 1 | 4.38 |
| CHEMBL442360 | — | — | 1 | 4.32 |
| CHEMBL58507 | — | — | 1 | 4.01 |
| CHEMBL58951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301229 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL58451 | — | Ki | = | 26000.0 | nM | 4.58 |
| CHEMBL58135 | — | Ki | = | 36000.0 | nM | 4.44 |
| CHEMBL60581 | — | Ki | = | 42000.0 | nM | 4.38 |
| CHEMBL442360 | — | Ki | = | 48300.0 | nM | 4.32 |
| CHEMBL58507 | — | Ki | = | 97000.0 | nM | 4.01 |
| CHEMBL58951 | — | Ki | = | 184000.0 | nM | - |