Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL682846

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of H-Ras Farnesyltransferase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Protein farnesyltransferase (CHEMBL2094108)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Ras farnesyltransferase: a new therapeutic target.
Leonard DM.
J Med Chem (1997) 40 : 2971 -2990
PubMed 9301658 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL62387 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL62387 IC50 = 11.0 nM 7.96