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Assay Detail

CHEMBL683059

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro binding affinity against GABA receptor in house fly
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Musca domestica
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

5-amino-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-3-[3H3]-methylsulfanyl-1H-pyrazole-4-carbonitrile (CTOM): synthesis and characterization of a novel and selective insect GABA receptor radioligand.
Meegalla SK, Doller D, Silver GM, Wisnewski N, Soll RM, Dhanoa D.
Bioorg Med Chem Lett (2003) 13 : 4035 -4037
PubMed 14592502 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.10 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL128970 1 8.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL128970 Ki = 8.0 nM 8.10