Assay Detail
Functional
CHEMBL683374
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Compound was tested for its antiviral activity against hepatitis B virus(DHBV) in duck fetal hepatocytes culture
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Anas sp. |
| Cell Type | Hepatocyte |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.96 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 7.00 |
| CHEMBL49260 | — | — | 1 | 5.70 |
| CHEMBL297708 | — | — | 1 | 5.70 |
| CHEMBL48519 | — | — | 1 | 5.70 |
| CHEMBL52288 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL49260 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL297708 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL48519 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL52288 | — | IC50 | = | 2000.0 | nM | 5.70 |