Assay Detail
Functional
CHEMBL683467
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Compound was evaluated for anti-HIV activity in acutely infected H9 Lymphocytes
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-AIDS agents. 33. Synthesis and anti-HIV activity of mono-methyl substituted 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.09 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 7.35 |
| CHEMBL304144 | — | — | 1 | 6.82 |
| CHEMBL269559 | — | — | 1 | - |
| CHEMBL431573 | — | — | 1 | - |
| CHEMBL305179 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | EC50 | = | 45.0 | nM | 7.35 |
| CHEMBL304144 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL269559 | — | EC50 | = | - | nM | - |
| CHEMBL431573 | — | EC50 | = | 0.000157 | nM | - |
| CHEMBL305179 | — | EC50 | = | 0.000423 | nM | - |