Assay Detail
Functional
CHEMBL683565
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In vitro inhibitory activity against lipid peroxidation in gerbils
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Gerbillinae |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and biological evaluation of novel antioxidants containing N-t-Butyl-N-hydroxylaminophenyl moieties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.08 | 5.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL73688 | — | — | 1 | 5.84 |
| CHEMBL76514 | — | — | 1 | 5.37 |
| CHEMBL307851 | — | — | 1 | 4.96 |
| CHEMBL51085 | EBSELEN | 3.0 | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL73688 | — | IC50 | = | 1440.0 | nM | 5.84 |
| CHEMBL76514 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL307851 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL51085 | EBSELEN | IC50 | = | 68900.0 | nM | 4.16 |