Assay Detail
Functional
CHEMBL683735
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Inhibitory concentration of compound against HIV-1 LAI strain in GHOST CXCR4 cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | GHOST CXCR4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.08 | 9.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18442 | PLERIXAFOR | 4.0 | 1 | 9.02 |
| CHEMBL145521 | — | — | 1 | 8.15 |
| CHEMBL3215409 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18442 | PLERIXAFOR | IC50 | = | 0.95 | nM | 9.02 |
| CHEMBL145521 | — | IC50 | = | 7.1 | nM | 8.15 |
| CHEMBL3215409 | — | IC50 | = | 86.0 | nM | 7.07 |