Assay Detail
Functional
CHEMBL684099
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Concentration required to inhibit viral replication in acutely infected H9 lymphocytes when tested for anti-HIV activity
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.04 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18974 | — | — | 1 | 5.12 |
| CHEMBL18688 | — | — | 1 | 5.04 |
| CHEMBL273327 | — | — | 1 | 5.02 |
| CHEMBL276943 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18974 | — | EC50 | = | 7590.0 | nM | 5.12 |
| CHEMBL18688 | — | EC50 | = | 9180.0 | nM | 5.04 |
| CHEMBL273327 | — | EC50 | = | 9530.0 | nM | 5.02 |
| CHEMBL276943 | — | EC50 | = | 10900.0 | nM | 4.96 |