Assay Detail
Binding
CHEMBL684229
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Concentration required to inhibit glucosamine-6-phosphate synthase (GFAT) isolated from Candida albicans
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Multisubstrate analogue inhibitors of glucosamine-6-phosphate synthase from Candida albicans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.47 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL88621 | — | — | 1 | 8.00 |
| CHEMBL39664 | SELFOTEL | 2.0 | 1 | 6.40 |
| CHEMBL285843 | — | — | 1 | 5.00 |
| CHEMBL274440 | AP-7 | — | 1 | - |
| CHEMBL29587 | — | — | 1 | - |
| CHEMBL28862 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL88621 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL39664 | SELFOTEL | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL285843 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL274440 | AP-7 | IC50 | = | 270000.0 | nM | - |
| CHEMBL29587 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL28862 | — | IC50 | = | 210000.0 | nM | - |