Assay Detail
Binding
CHEMBL685089
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity for L1210 Glycinamide ribotide formyltransferase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antifolate properties of 10-alkyl-5,10-dideaza analogues of methotrexate and tetrahydrofolic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.10 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279508 | — | — | 1 | 6.30 |
| CHEMBL162414 | — | — | 1 | 6.18 |
| CHEMBL162701 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279508 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL162414 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL162701 | — | IC50 | = | 1500.0 | nM | 5.82 |