Assay Detail
Binding
CHEMBL686166
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Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Schistosoma japonicum |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and glutathione S-transferase structure-affinity relationships of nonpeptide and peptidase-stable glutathione analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.99 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1543 | GLUTATHIONE | 3.0 | 1 | 7.70 |
| CHEMBL75497 | — | — | 1 | 5.28 |
| CHEMBL73552 | — | — | 1 | 5.00 |
| CHEMBL76285 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1543 | GLUTATHIONE | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL75497 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL73552 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL76285 | — | IC50 | = | 1800000.0 | nM | - |