Assay Detail
Functional
CHEMBL686568
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Cytotoxicity against H.Ep cells in the presence of 0.1 ug/mL pentostatin.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEp-2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of 2-fluoro-8-azaadenosine and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL605060 | — | — | 1 | 5.70 |
| CHEMBL3143937 | — | — | 1 | - |
| CHEMBL2368663 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL605060 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL3143937 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL2368663 | — | IC50 | > | 20000.0 | nM | - |