Assay Detail
Functional
CHEMBL686782
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for H1-antihistamine activity in guinea pig ileum.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Studies on 1,2,3-triazoles. 13. (Piperazinylalkoxy) [1]benzopyrano[2,3-d]-1,2,3-triazol-9(1H)-ones with combined H1-antihistamine and mast cell stabilizing properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.37 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL312083 | — | — | 1 | 7.80 |
| CHEMBL306807 | — | — | 1 | 7.20 |
| CHEMBL73265 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL312083 | — | Kd | = | 15.85 | nM | 7.80 |
| CHEMBL306807 | — | Kd | = | 63.1 | nM | 7.20 |
| CHEMBL73265 | — | Kd | = | 79.43 | nM | 7.10 |