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Assay Detail

CHEMBL687803

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
compound was tested for antiviral activity against HRV-2 in cell culture
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies.
Dragovich PS, Webber SE, Babine RE, Fuhrman SA, Patick AK, Matthews DA, Reich SH, Marakovits JT, Prins TJ, Zhou R, Tikhe J, Littlefield ES, Bleckman TM, Wallace MB, Little TL, Ford CE, Meador JW, Ferre RA, Brown EL, Binford SL, DeLisle DM, Worland ST.
J Med Chem (1998) 41 : 2819 -2834
PubMed 9667971 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19648 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19648 EC50 = 1600.0 nM 5.80