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Assay Detail

CHEMBL687935

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Functional
Compound was tested for antiviral activity against wild-type Towne virus of HCMV in plaque reduction assay using HFF cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HFF
Confidence 1 — Organism
Curated By Intermediate

Target

HFF (CHEMBL614071)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles.
Gudmundsson KS, Tidwell J, Lippa N, Koszalka GW, van Draanen N, Ptak RG, Drach JC, Townsend LB.
J Med Chem (2000) 43 : 2464 -2472
PubMed 10882374 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.21 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL610088 1 6.64
CHEMBL473894 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL610088 IC50 = 230.0 nM 6.64
CHEMBL473894 IC50 = 1700.0 nM 5.77