Assay Detail
Functional
CHEMBL687991
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Compound was tested for antiviral activity against HCMV in viral cytopathic effect (CPE) assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.47 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL610088 | — | — | 1 | 7.30 |
| CHEMBL311260 | — | — | 1 | 7.30 |
| CHEMBL605480 | — | — | 1 | 7.00 |
| CHEMBL312038 | — | — | 1 | 7.00 |
| CHEMBL473894 | — | — | 1 | 6.52 |
| CHEMBL609189 | — | — | 1 | 6.22 |
| CHEMBL610659 | — | — | 1 | 6.10 |
| CHEMBL608010 | — | — | 1 | 6.00 |
| CHEMBL606433 | — | — | 1 | 5.64 |
| CHEMBL609782 | — | — | 1 | 5.64 |
| CHEMBL608011 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL610088 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL311260 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL605480 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL312038 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL473894 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL609189 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL610659 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL608010 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL606433 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL609782 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL608011 | — | IC50 | > | 10000.0 | nM | - |