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Assay Detail

CHEMBL688244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration of compound that increased the percentage of formazan production in HRV-2 virus infected cells to that of untreated control cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.
Dragovich PS, Webber SE, Babine RE, Fuhrman SA, Patick AK, Matthews DA, Lee CA, Reich SH, Prins TJ, Marakovits JT, Littlefield ES, Zhou R, Tikhe J, Ford CE, Wallace MB, Meador JW, Ferre RA, Brown EL, Binford SL, Harr JE, DeLisle DM, Worland ST.
J Med Chem (1998) 41 : 2806 -2818
PubMed 9667970 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19648 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19648 EC50 = 1600.0 nM 5.80