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Assay Detail

CHEMBL688249

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration was measured on HRV-89 infected H1- HeLa cells by protection assay.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements.
Webber SE, Okano K, Little TL, Reich SH, Xin Y, Fuhrman SA, Matthews DA, Love RA, Hendrickson TF, Patick AK, Meador JW, Ferre RA, Brown EL, Ford CE, Binford SL, Worland ST.
J Med Chem (1998) 41 : 2786 -2805
PubMed 9667969 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95007 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95007 EC50 = 2200.0 nM 5.66