Assay Detail

CHEMBL688552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

In vitro inhibitory activity against opioid receptor in Guinea pig ileum

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Tissue	Ileum
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Synthesis, antinociceptive activity, and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols.

Judd DB, Brown DS, Lloyd JE, McElroy AB, Scopes DI, Birch PJ, Hayes AG, Sheehan MJ.
J Med Chem (1992) 35 : 48 -56
PubMed 1310115 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.30	9.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL279968	ETHYLKETOCYCLAZOCINE	—	1	9.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL279968	ETHYLKETOCYCLAZOCINE	IC50	=	0.5	nM	9.30