Assay Detail
Functional
CHEMBL688960
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Compound was evaluated for anti-HIV activity and the concentration that inhibits uninfected H9 cell growth by 50%
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-AIDS agents. 33. Synthesis and anti-HIV activity of mono-methyl substituted 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.47 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304144 | — | — | 1 | 4.48 |
| CHEMBL269559 | — | — | 1 | 4.46 |
| CHEMBL303397 | — | — | 1 | - |
| CHEMBL431573 | — | — | 1 | - |
| CHEMBL305179 | — | — | 1 | - |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304144 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL269559 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL303397 | — | IC50 | > | 157000.0 | nM | - |
| CHEMBL431573 | — | IC50 | > | 157000.0 | nM | - |
| CHEMBL305179 | — | IC50 | > | 157000.0 | nM | - |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1875000.0 | nM | - |