Assay Detail
Functional
CHEMBL688966
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit uninfected H9 cell growth
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-AIDS agents part 41: synthesis and anti-HIV activity of 3',4'-di-o-(-)-camphanoyl-(+)-cis-khellactone (DCK) lactam analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.46 | 4.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6396 | — | — | 1 | 4.55 |
| CHEMBL269559 | — | — | 1 | 4.46 |
| CHEMBL268653 | — | — | 1 | 4.38 |
| CHEMBL6758 | — | — | 1 | - |
| CHEMBL6703 | — | — | 1 | - |
| CHEMBL266430 | — | — | 1 | - |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6396 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL269559 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL268653 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL6758 | — | IC50 | > | 157000.0 | nM | - |
| CHEMBL6703 | — | IC50 | = | 125000.0 | nM | - |
| CHEMBL266430 | — | IC50 | = | 104000.0 | nM | - |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1875000.0 | nM | - |