Assay Detail
Functional
CHEMBL688969
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Evaluated for the anti-HIV activity against HIV-1 replication in mock-infected H9 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.46 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL55887 | — | — | 1 | 4.54 |
| CHEMBL54355 | — | — | 1 | 4.47 |
| CHEMBL54519 | — | — | 1 | 4.43 |
| CHEMBL292426 | — | — | 1 | 4.43 |
| CHEMBL54100 | — | — | 1 | 4.41 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL55887 | — | IC50 | = | 28600.0 | nM | 4.54 |
| CHEMBL54355 | — | IC50 | = | 33600.0 | nM | 4.47 |
| CHEMBL54519 | — | IC50 | = | 37400.0 | nM | 4.43 |
| CHEMBL292426 | — | IC50 | = | 36900.0 | nM | 4.43 |
| CHEMBL54100 | — | IC50 | = | 38600.0 | nM | 4.41 |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1873000.0 | nM | - |