Assay Detail
Functional
CHEMBL689056
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for the ability to inhibitH+/K+ -ATPase formation in rabbit gastric glands.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Stomach |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiulcer agents. 5. Inhibition of gastric H+/K(+)-ATPase by substituted imidazo[1,2-a]pyridines and related analogues and its implication in modeling the high affinity potassium ion binding site of the gastric proton pump enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.38 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296417 | — | — | 1 | 6.00 |
| CHEMBL45835 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296417 | — | IC50 | = | 990.0 | nM | 6.00 |
| CHEMBL45835 | — | IC50 | = | 17500.0 | nM | 4.76 |