Assay Detail
Functional
CHEMBL689115
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration required to inhibit uninfected H9 cell growth by 50%
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-AIDS agents. Part 47: Synthesis and anti-HIV activity of 3-substituted 3',4'-Di-O-(S)-camphanoyl-(3'R,4'R)-(+)-cis-khellactone derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.89 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308801 | — | — | 1 | 5.50 |
| CHEMBL430615 | — | — | 1 | 5.48 |
| CHEMBL310494 | — | — | 1 | 5.47 |
| CHEMBL409338 | — | — | 1 | 4.48 |
| CHEMBL269559 | — | — | 1 | 4.46 |
| CHEMBL310254 | — | — | 1 | 4.45 |
| CHEMBL306336 | — | — | 1 | 4.37 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308801 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL430615 | — | IC50 | = | 3340.0 | nM | 5.48 |
| CHEMBL310494 | — | IC50 | = | 3380.0 | nM | 5.47 |
| CHEMBL409338 | — | IC50 | = | 32810.0 | nM | 4.48 |
| CHEMBL269559 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL310254 | — | IC50 | = | 35350.0 | nM | 4.45 |
| CHEMBL306336 | — | IC50 | = | 43010.0 | nM | 4.37 |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1875000.0 | nM | - |