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Assay Detail

CHEMBL689333

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Binding
Compound was tested for binding affinity towards HPPK Receptor with Mg 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies.
Shi G, Blaszczyk J, Ji X, Yan H.
J Med Chem (2001) 44 : 1364 -1371
PubMed 11311059 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 5.85 6.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1928286 1 6.33
CHEMBL603799 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1928286 Kd = 470.0 nM 6.33
CHEMBL603799 Kd = 4250.0 nM 5.37