Assay Detail
Functional
CHEMBL689339
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
DNA helicase/primase complex protein (CHEMBL4380) ↗| Type | SINGLE PROTEIN |
| Organism | Herpes simplex virus (type 1 / strain 17) |
Publication
Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.23 | 4.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51613 | — | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51613 | — | IC50 | = | 59000.0 | nM | 4.23 |