Assay Detail
Functional
CHEMBL689847
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro activity against H157 non-small-cell lung tumor line (non-SCLC) cultures.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H157 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Terminally alkylated polyamine analogues as chemotherapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.14 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL447829 | — | — | 1 | 6.40 |
| CHEMBL40258 | — | — | 1 | 6.30 |
| CHEMBL33387 | — | — | 1 | 6.16 |
| CHEMBL41629 | — | — | 1 | 5.68 |
| CHEMBL416078 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL447829 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL40258 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL33387 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL41629 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL416078 | — | IC50 | > | 10000.0 | nM | - |