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Assay Detail

CHEMBL689935

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity as 50% inhibitory concentration against HSV-1
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 1
Confidence 1 — Organism
Curated By Intermediate

Target

Human alphaherpesvirus 1 (CHEMBL377)
Type ORGANISM
Organism Human alphaherpesvirus 1

Publication

Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.
Krawczyk SH, Nassiri MR, Kucera LS, Kern ER, Ptak RG, Wotring LL, Drach JC, Townsend LB.
J Med Chem (1995) 38 : 4106 -4114
PubMed 7562946 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.98 8.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3143101 2 8.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3143101 IC50 = 3.7 nM 8.43
CHEMBL3143101 IC50 = 30.0 nM 7.52