Assay Detail
Functional
CHEMBL690085
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against herpes simplex virus type 1(HSV-1) ELISA method
15
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and evaluation of certain thiosangivamycin analogs as potential inhibitors of cell proliferation and human cytomegalovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 15 | 5.10 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99668 | TOYOCAMYCIN | — | 2 | 6.40 |
| CHEMBL2092972 | — | — | 1 | 5.72 |
| CHEMBL132669 | — | — | 1 | 5.58 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.46 |
| CHEMBL3143100 | — | — | 1 | 5.35 |
| CHEMBL3350229 | — | — | 1 | 5.33 |
| CHEMBL132208 | — | — | 1 | 5.22 |
| CHEMBL3143096 | — | — | 1 | 5.09 |
| CHEMBL336782 | — | — | 1 | 4.85 |
| CHEMBL338681 | — | — | 1 | 4.68 |
| CHEMBL3143103 | — | — | 1 | 4.55 |
| CHEMBL130555 | — | — | 1 | 4.39 |
| CHEMBL134202 | — | — | 1 | 4.24 |
| CHEMBL3142825 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99668 | TOYOCAMYCIN | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL2092972 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL132669 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL182 | GANCICLOVIR | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL3143100 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL3350229 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL132208 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL3143096 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL336782 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL338681 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL3143103 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL99668 | TOYOCAMYCIN | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL130555 | — | IC50 | = | 41000.0 | nM | 4.39 |
| CHEMBL134202 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL3142825 | — | IC50 | = | 320000.0 | nM | - |