Assay Detail
Functional
CHEMBL690098
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Compound was tested for cytotoxicity against colon adenocarcinoma
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Plant antitumor agents. 31. The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.06 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.75 |
| CHEMBL34316 | CALYCOPTERONE | — | 2 | 6.62 |
| CHEMBL33256 | CHRYSOSPLENOL B | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL34316 | CALYCOPTERONE | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL34316 | CALYCOPTERONE | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL33256 | CHRYSOSPLENOL B | IC50 | = | 14200.0 | nM | 4.85 |