Assay Detail
Binding
CHEMBL690418
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Tested for inhibitory activity against HIV protease
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
A bis-[N-3-(1-hydroxy-1-methyl-ethyl)-benzyl)-cyclic urea as a HIV protease inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.19 | 9.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL21145 | DMP-323 | — | 1 | 9.51 |
| CHEMBL285417 | — | — | 1 | 9.40 |
| CHEMBL103013 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL21145 | DMP-323 | Ki | = | 0.31 | nM | 9.51 |
| CHEMBL285417 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL103013 | — | Ki | = | 2.2 | nM | 8.66 |