Assay Detail
Functional
CHEMBL690474
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Inhibitory concentration against HT-29 colon cancer cell line
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.55 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320647 | — | — | 1 | 7.05 |
| CHEMBL101871 | — | — | 1 | 6.85 |
| CHEMBL101299 | — | — | 1 | 6.35 |
| CHEMBL369474 | PSOROSPERMIN | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320647 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL101871 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL101299 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL369474 | PSOROSPERMIN | IC50 | = | 1110.0 | nM | 5.96 |