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Assay Detail

CHEMBL690680

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for reversible inhibition against gastric H+/K+-ATPase isolated from porcine gastric microsomes; value ranges from 3-10 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Sus scrofa
Tissue Stomach
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of bone resorption by H+/K(+)-ATPase inhibitors.
Sarges R, Gallagher A, Chambers TJ, Yeh LA.
J Med Chem (1993) 36 : 2828 -2830
PubMed 8410997 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95108 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95108 IC50 = 3000.0 nM 5.52