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Assay Detail

CHEMBL690851

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Activity against H157 non-SCLC cells in culture
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H157
Confidence 1 — Organism
Curated By Intermediate

Target

NCI-H157 (CHEMBL614783)
Type CELL-LINE
Organism Homo sapiens

Publication

Terminally alkylated polyamine analogues as chemotherapeutic agents.
Casero RA, Woster PM.
J Med Chem (2001) 44 : 1 -26
PubMed 11141084 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.03 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL33387 1 6.10
CHEMBL86940 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL33387 IC50 = 800.0 nM 6.10
CHEMBL86940 IC50 = 1100.0 nM 5.96