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Assay Detail

CHEMBL690901

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition constant against HSV-1 TK
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism herpes simplex virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Russ P, Schelling P, Scapozza L, Folkers G, Clercq ED, Marquez VE.
J Med Chem (2003) 46 : 5045 -5054
PubMed 14584954 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.20 4.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL146350 1 4.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL146350 Ki = 62900.0 nM 4.20