Assay Detail
Functional
CHEMBL690923
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Concentration which caused 50% loss of the monolayer present around the viral plaques in uM
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.34 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL329723 | — | — | 1 | 6.92 |
| CHEMBL29711 | APHIDICOLIN | — | 1 | 6.23 |
| CHEMBL100106 | — | — | 1 | 6.20 |
| CHEMBL98369 | — | — | 1 | 6.18 |
| CHEMBL99296 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL329723 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL29711 | APHIDICOLIN | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL100106 | — | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL98369 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL99296 | — | IC50 | = | 690.0 | nM | 6.16 |