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Assay Detail

CHEMBL691286

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against HT-29 human colon cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Intermediate

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines.
Wells G, Berry JM, Bradshaw TD, Burger AM, Seaton A, Wang B, Westwell AD, Stevens MF.
J Med Chem (2003) 46 : 532 -541
PubMed 12570375 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.08 4.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47875 1 4.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47875 IC50 = 83700.0 nM 4.08