Assay Detail
Functional
CHEMBL691477
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In vitro inhibitory activity against proliferation of HBV viral cell
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and comparative evaluation of two antiviral agents: beta-L-Fd4C and beta-D-Fd4C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.10 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38700 | ELVUCITABINE | 2.0 | 1 | 8.10 |
| CHEMBL109831 | DEXELVUCITABINE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38700 | ELVUCITABINE | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL109831 | DEXELVUCITABINE | EC50 | < | 300.0 | nM | - |