Assay Detail
Functional
CHEMBL691544
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The compound evaluated for Cytotoxic activity against multi drug resistant HUT 78 cells (the results were obtained after 48 hr treatment)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HuT78 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Programmed cell death (PCD) associated with the stilbene motif of arotinoids: discovery of novel apoptosis inducer agents possessing activity on multidrug resistant tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.78 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90947 | — | — | 1 | 5.30 |
| CHEMBL90624 | — | — | 1 | 4.66 |
| CHEMBL90623 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90947 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL90624 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL90623 | — | IC50 | = | 43000.0 | nM | 4.37 |