Assay Detail
Binding
CHEMBL691617
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Binding affinity towards human H1 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Current and novel approaches to the drug treatment of schizophrenia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.05 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285802 | ZOTEPINE | 2.0 | 1 | 9.21 |
| CHEMBL715 | OLANZAPINE | 4.0 | 1 | 8.25 |
| CHEMBL716 | QUETIAPINE | 4.0 | 1 | 7.68 |
| CHEMBL85 | RISPERIDONE | 4.0 | 1 | 7.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285802 | ZOTEPINE | Ki | = | 0.62 | nM | 9.21 |
| CHEMBL715 | OLANZAPINE | Ki | = | 5.6 | nM | 8.25 |
| CHEMBL716 | QUETIAPINE | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL85 | RISPERIDONE | Ki | = | 88.0 | nM | 7.06 |