Assay Detail
Functional
CHEMBL691794
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Inhibition of HUVEC adhesion to fibrinogen-coated plates
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design of a new class of orally active fibrinogen receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.64 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265628 | — | — | 1 | 4.64 |
| CHEMBL82264 | — | — | 1 | - |
| CHEMBL82231 | — | — | 1 | - |
| CHEMBL309250 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265628 | — | IC50 | = | 22700.0 | nM | 4.64 |
| CHEMBL82264 | — | IC50 | > | 1650000.0 | nM | - |
| CHEMBL82231 | — | IC50 | > | 2400000.0 | nM | - |
| CHEMBL309250 | — | IC50 | > | 2500000.0 | nM | - |