Assay Detail
Functional
CHEMBL692482
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of estrogen production in hamster ovarian tissue
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and aromatase inhibitory activity of novel 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane- and -[3.1.1]heptane-2,4- diones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.64 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27467 | — | — | 1 | 7.16 |
| CHEMBL281947 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27467 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL281947 | — | IC50 | = | 780.0 | nM | 6.11 |