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Assay Detail

CHEMBL692652

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro antiviral activity against Herpes simplex virus type 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 1
Confidence 1 — Organism
Curated By Intermediate

Target

Human alphaherpesvirus 1 (CHEMBL377)
Type ORGANISM
Organism Human alphaherpesvirus 1

Publication

Synthesis and antiviral activity of novel acyclic nucleoside analogues of 5-(1-azido-2-haloethyl)uracils.
Kumar R, Sharma N, Nath M, Saffran HA, Tyrrell DL.
J Med Chem (2001) 44 : 4225 -4229
PubMed 11708924 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.78 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3142423 1 7.22
CHEMBL3143144 1 6.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3142423 EC50 = 60.0 nM 7.22
CHEMBL3143144 EC50 = 460.0 nM 6.34